This repository contains tutorial documentation for stEDGE, an edge-guided framework for multiscale reconstruction of hierarchical spatial domains and transition interfaces in spatial transcriptomics.

People communicate with each other, sometimes face to face, sometimes with a text message or phone call. Cells also ...

Life in multicellular organisms depends on the precise orchestration of cell-cell communication. Key processes in development, physiological functions, immune responses, and disease progression are ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...

An effective and efficient method for joint analyses of multiple spatial transcriptomics datasets. We develop INSPIRE, a deep learning-based method for integrating and interpreting multiple spatial ...

The complex landscape of cardiovascular diseases encompasses a wide range of related pathologies arising from diverse molecular mechanisms and exhibiting heterogeneous phenotypes. This variety of ...

Technological advances in characterizing molecular heterogeneity at the single cell level have ushered in a deeper understanding of the biological diversity of cells present in tissues including ...

Since their early association with atopic disease, granulocytes, particularly eosinophils, have been widely used as biomarkers, yet the mechanisms underlying their role in airway and atopic ...

Cell-based therapies hold great promise for treating late-stage retinal degenerative diseases. However, photoreceptor cell transplantation has been limited by poor cellular integration, suggesting ...

𝐀𝐈 / 𝐁𝐢𝐨𝐢𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐜𝐬 𝐓𝐨𝐨𝐥𝐬 𝐟𝐨𝐫 𝐕𝐢𝐫𝐭𝐮𝐚𝐥 𝐂𝐞𝐥𝐥 𝟏 ...

NASA collects vast quantities of data about stars, planets and other objects, the Sun, our Earth, and even cells! This information is stored in a number of topical archives. Here we collect together ...