ascopubs.org

Are Needs Assessments Cost Effective in Reducing Distress Among Patients With Cancer? A Randomized Controlled Trial Using the Distress Thermometer and Problem List

We conducted an unblinded, two-arm, parallel randomized controlled trial at two sites among patients starting radiotherapy or chemotherapy. The intervention group completed the DT&PL, rating distress ...
Tobacco Control

Effectiveness of a school-based health education intervention on tobacco use intention among adolescents: a cluster-randomised controlled trial

Background Adolescence is a critical period for tobacco initiation, and intention to use tobacco strongly predicts uptake. In ...
The New England Journal of Medicine

Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH

Pegozafermin is a long-acting glycopegylated (pegylated with the use of site-specific glycosyltransferases) fibroblast growth factor 21 (FGF21) analogue in development for the treatment of ...
ascopubs.org

Efficacy and safety of trastuzumab deruxtecan for metastatic HER2+ and HER2-low breast cancer: A systematic review and meta-analysis of randomised controlled trials.

A randomized, double-blind, three-arm, parallel group, phase 1 study to assess the pharmacokinetics, safety, and tolerability of PERT-IJS following a single dose of 420 mg intravenous infusion ...
BMJ Open

Practical guide for determining whether healthcare providers are research participants in cluster randomised trials

Introduction In cluster randomised trials (CRT), groups (rather than individuals) are randomised to intervention and control conditions. Since the publication of the Ottawa Statement on the Ethical ...