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Cells balance protein production and removal through passive adaptation
Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but ...
In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...
Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells. A ...
The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...
Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.
Cell-line development enhances biopharmaceutical production capacity and quality, but complex biologics like bsAbs and ADCs present new challenges.
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