Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...
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Scientists identify a non-coding gene that directly controls how big cells grow
The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.
(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...
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