When laboratory mice step out of their plastic cages and into real soil, their behavior changes so dramatically that it forces a rethink of what stress, health and even “normal” really mean. The story ...

When scientists opened the doors of a research facility and let carefully bred lab mice loose into a fenced field, they ...

New research suggests that the commonly used ‘lab mouse’ may display behaviors entirely distinct from their wild-derived counterparts, prompting new considerations for the future of animal-based ...

In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Genetically altered mice are valuable tools in biomedical research. The Mutant Mouse Resource and Research Center, located at UC Davis and supported by a grant from NIH, has been providing a national ...

Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...

One of those genes encodes the enzyme DHDDS, part of the pathway that glycosylates proteins in higher cells. Retinitis pigmentosa from DHDDS mutations is called RP59. This is a recessive genetic ...