When scientists opened the doors of a research facility and let carefully bred lab mice loose into a fenced field, they ...

When laboratory mice step out of their plastic cages and into real soil, their behavior changes so dramatically that it ...

New research suggests that the commonly used ‘lab mouse’ may display behaviors entirely distinct from their wild-derived counterparts, prompting new considerations for the future of animal-based ...

In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

In the wild, a mouse or rat leads a precarious life. In the city, they dodge traps, poisons, and broom-wielding humans. In the countryside, they face owls, shotguns, and more poison. As Australia’s ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

Researchers showed that a severe drop in NAD+—a core energy molecule—drives Alzheimer’s pathology in both human brains and mouse models.