A new adenoviral vector (Ad-GFAP-GDNF) (Ad=adenovirus, GFAP=glial fibrillary acidic protein, GDNF=glial cell line-derived neurotrophic factor) was constructed in which (i) the E1,E3/E4 regions of Ad5 ...

GDNF is an important factor for the survival, regeneration and maintenance of DA-ergic midbrain neurons, 1, 2 and an increase in the GDNF levels has been suggested to be beneficial for Parkinson's ...

Elevated levels of the neuroprotein GDNF may help fight the weight gain and health problems associated with a high-fat diet, new research finds. More than one-third of people in the US are obese.

Young people who abuse methamphetamines may put themselves at risk of Parkinson’s-like movement disorders later in life, a new animal study suggests. In experiments with mice, scientists found that ...

Pfizer has bought itself an exclusive, worldwide option to license MedGenesis’ glial cell line-derived neurotrophic factor (GDNF) protein and convection enhanced delivery (CED) technology for use in ...

A collaboration to develop a new class of small molecule mimetics for the treatment of Parkinson's disease and other indications. Argobio will fund the development of this innovative project up to €3 ...

A molecule that has long been a source of hope as a potential Parkinson’s disease therapy will get a new chance to show its benefit. A team led by Krystof Bankiewicz at the University of California, ...

Pfizer has struck a deal with MedGenesis Therapeutix to license its glial cell line-derived neurotrophic factor (GDNF) protein and convection enhanced delivery (CED) technology to investigate ...

MedGenesis Therapeutix ("MedGenesis"), a private biopharmaceutical company focused on central nervous system (“CNS”) treatments has inked a deal with Amgen (NASDAQ: AMGN) to license its glial cell ...

Northwestern University neuroscientists have overcome a major obstacle in gene therapy research. They've devised a method that will safely deliver and regulate expression of therapeutic genes ...

GAINESVILLE, Fla. — A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according ...