The G1/S transition in normal cells is a thoroughly controlled checkpoint where the important decision to initiate DNA-replication or not is taken (Draetta, 1994; Weinberg, 1995). As has been obvious ...
Prostatic adenocarcinoma is the most commonly diagnosed malignancy in the US, and is a leading cause of cancer death in men (Jemal et al, 2006). This tumor type is dependent on androgen for growth and ...
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