T cells are a fundamental component of the adaptive immune system. Ligation of the T cell antigen receptor (TCR) with antigenic peptide bound to major histocompatibility complex molecules on ...
CD3e molecule, epsilon (CD3E), is a single-pass type I membrane glycoprotein found on T cells. It contains one Ig-like (immunoglobulin-like) domain and one ITAM domain. CD3E, along with CD3-gamma, CD3 ...
We report a novel defect in the CD3δ gene in three members of a kindred with a form of severe combined immunodeficiency (SCID) characterized by the absence of T cells but normal numbers of B cells ...
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